12 mg/kg/dose IV once daily after initial treatment with lipid amphotericin B or an echinocandin for patients who are unlikely to have a fluconazole-resistant. Fluconazole, the first of a new subclass of synthetic triazole antifungal agents, is available as a sterile solution for intravenous use in flexible plastic containers. Fluconazole is also available for oral therapy. The patient should be switched from dosing by the intravenous route to dosing by the oral route as soon as.
Diflucan iv - something is
Clarithromycin: Severe Coadministration is contraindicated. Famotidine; Ibuprofen: Moderate Fluconazole is an inhibitor of cytochrome P isoenzyme 2C9, which is the isoenzyme responsible for the metabolism of ibuprofen. The FDA-approved dosage is mg IV on day 1, followed by to mg IV once daily for 10 to 12 weeks after cerebrospinal fluid culture becomes negative. Liver-function tests should be monitored. The presence of other medical problems may affect the use of this medicine. Patients should be monitored for increased anticholinergic effects if these drugs are used concomitantly; dosage adjustments of darifenacin may be necessary. If signs and symptoms of hepatotoxicity develop, fluconazole therapy should be stopped. Diflucan reviews. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Amphotericin B lipid complex ABLC : Moderate Theoretically, azole antifungals could interfere with the action of amphotericin B by depleting difludan binding sites. Dronabinol: Major Diflucann caution if coadministration of dronabinol with fluconazole is necessary, and monitor for an increase in dronabinol-related adverse reactions e. Although QT interval prolongation has not been reported with gemtuzumab, it has been reported with other drugs that contain calicheamicin.
Diflucan iv - something is
Apomorphine: Major Due to the potential for QT prolongation and torsade de pointes TdP , caution is advised when administering fluconazole with apomorphine. Coadministration of fluconazole with quinidine may result in elevated plasma concentrations of quinidine, causing an increased risk for adverse events, such as QT prolongation. Fluconazole is an inhibitor of the hepatic isoenzyme CYP3A4; ritonavir, paritaprevir, and dasabuvir minor are metabolized by this enzyme. Experts have estimated, based on limited data of concentrations in breast milk, that an exclusively breast-fed infant whose mother was receiving fluconazole mg daily would receive a maximum dose of 0. Glimepiride: Moderate Fluconazole should be used cautiously with glimepiride. Use caution when fluconazole is administered to a breast-feeding woman. Acalabrutinib: Major Decrease the acalabrutinib dose to mg PO once daily if coadministered with fluconazole. Hydrocodone; Phenylephrine: Synthroid empty stomach
a substrate of and primarily diflucwn by CYP3A4. Further adjustments may be needed depending upon the clinical situation.