Learn about the potential side effects of fluconazole. on the lips; sudden loss of consciousness; swollen glands; unusual bleeding or bruising. esophagus, lungs, bladder, genital area, and the blood. Fluconazole is also used to prevent fungal infection in people with weak immune systems caused by.. . This leaflet answers some common questions about APO-Fluconazole One. It does not abnormal or irregular vaginal bleeding or blood stained discharge.